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dpp-4_inhibitors [TUSOM | Pharmwiki]
Transferring fecal microbiota from semaglutide-treated donors to antibiotic-depleted pseudo-germ-free obese mice partially reproduced metabolic benefits, such as lower fasting insulin and improved insulin resistance and lipids, implicating microbiome-mediated mechanisms [88]
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These residues are located within the upper and central regions of the TM2 and TM3 bundle and have been recurrently associated with ligand recognition in active-state GLP-1R structures (Zhao et al., 2020)
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