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The SGLT2i also improve beta cell function, but they do so by reversal of glucotoxicity (31)
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Our previous study, BARI-OPTIMISE, selectively recruited participants with suboptimal weight loss after MBS who also had a blunted meal-stimulated GLP-1 response, based on observational study data correlating higher native postprandial GLP-1 levels to higher %WL after MBS
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