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separate doses by at least 4 hours and monitor thyroid function Potential effects on anticonvulsants and amiodarone should also be considered Important safety advice includes: Report severe or persistent side effects to your prescriber immediately Contact your GP urgently if you experience severe abdominal pain, persistent vomiting, signs of gallbladder problems (pain in the upper right abdomen, yellowing of skin or eyes), reduced urine output, or symptoms of liver injury Do not use these medications if pregnant or planning pregnancy—discuss contraception with your healthcare provider Inform all healthcare professionals about weight loss medication use, especially before surgery or when prescribed new medications Report suspected adverse drug reactions to the MHRA Yellow Card Scheme (online at yellowcard.mhra.gov.uk or via the Yellow Card app) to contribute to ongoing safety monitoring Weight loss medications require ongoing medical supervision

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For specific guidance based on your formulation and pharmacy, check the label or contact your pharmacy directly