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There are a lot of questions that still need to be answered, and that’s a neat thing about science – one good hypothesis or question deserves three more
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Our previous study also showed that INKO mice have a different gut microbiota composition than their counterparts under a regular chow diet, suggesting that intestinal NAD + biosynthesis is involved in maintaining gut microbiota homeostasis and possibly contributing to the reduced GLP-1 production (unpublished data)
